Understanding Medication-Assisted Treatment Options
Traditionally, rehab programs relied on therapy and non-medication related treatments. The backbone of most programs was cognitive-behavioral therapy (CBT). While CBT still maintains a central role in treatment, MAT options have been shown to significantly improve the chances of people recovering from addiction.
Addiction involves the following cycle: euphoria, crash, and craving. This cycle hinders a person’s ability to participate in society and can be harmful to their social, financial and occupational functioning.
Medications used for MAT are safe and effective when used correctly by trained physicians.
What Is Vivitrol?
Vivitrol is a once-monthly injection of naltrexone. Naltrexone blocks access to opioid receptors, so they cannot be activated. Since addictive opioids work by activating opioid receptors, blockage by naltrexone can prevent the drug from affecting the user.
For example, someone receives Vivitrol shots each month, and they try to take heroin. They pay for the heroin, administer it, and it has no effect. They can still take the drug, but it will not produce euphoria (pleasurable feelings) and reinforce further administration. In effect, the person has no reason to continue using heroin.
Vivitrol works to block euphoria from alcohol as well. In terms of dosage, Vivitrol is 380 milligrams of naltrexone administered as a once-monthly injection.
Vivitrol can only be given to someone who has been completely sober from opioids for 7-10 days, and this must be proven via urinalysis testing. Some clinicians may administer a test dose of oral naltrexone to ensure sobriety.
If someone has opioids in their system and receives Vivitrol, it will precipitate dangerous withdrawal symptoms. Since Vivitrol continues to release for one month, the withdrawal cannot be reversed. Precipitated withdrawal can be life-threatening.
Therefore, Vivitrol is only an option for someone who has completed opioid detox. Someone receiving Vivitrol will also be unable to use opioid medications for pain, including for surgery.
What Is Suboxone?
Suboxone is a combination of the drugs buprenorphine and naloxone. Buprenorphine is a partial opioid agonist, and naloxone is an antagonist but works differently than Vivitrol.
Since buprenorphine is a partial opioid agonist, it can be used by people who have not fully detoxed from opioids.
The naloxone component blocks opioid receptors but is only activated when someone tries to abuse Suboxone by crushing it for snorting or injecting. Naloxone does not absorb well in the stomach but will block opioid receptors if taken in other ways. Therefore, the addition of naloxone prevents illicit abuse of Suboxone.
Suboxone comes as tablets or sublingual (Suboxone strips) film. It is available as a generic medication and is taken once daily. Some may ask, “What is Suboxone used for?” Suboxone is used for OUD only and not AUD.